NAD IV Therapy
NAD IV Therapy
Reset, Recover, and Restore Treatments
What on earth is nicotinamide adenine dinucleotide?
Nicotinamide adenine dinucleotide (NAD+/NADH) was first discovered during yeast fermentation. Since its discovery, it has been found that NAD (nicotinamide adenine dinucleotide) is a major cofactor that partakes in virtually all cellular reactions. These include DNA repair, immune system function, ATP production, and a circadian clock function. NAD+ promotes energy production and enables cells to work properly. Dysregulation of the NAD+ levels has been associated with metabolic diseases and aging-related diseases, including neurodegeneration, defective immune responses, and cancer.
Introduction to NAD+
Ideally, NAD+ is in a homeostatic status of biosynthesis, consumption, recycling, and degradation at both cellular and systemic levels. Human cells can synthesize NAD+ de novo from tryptophan by the kynurenine pathway or from nicotinic acid (NA) by the Preiss‐Handler pathway. However, most NAD+ is recycled from nicotinamide (NAM), NA, nicotinamide riboside (NR), and nicotinamide mononucleotide (NMN) in the salvage pathway to maintain the cellular NAD+ levels. NAD+ can be reduced into NADH in various metabolic processes, including glycolysis, fatty acid oxidation, and the Krebs cycle.
Physiological benefits of having high NAD+ in the body:
- Optimal mitochondrial functioning
- Crucial biochemical element in energy production and muscle function
- Having enough NAD+ in the body prevents from muscle atrophy, fatigue and exhaustion
- Optimal brain function and prevention of neurodegeneration
- Optimal sleep-wake cycle and maintenance of natural circadian rhythms
- Protection from oxidative stress and inflammation
- Cellular survival and oxygen production Slowed aging and longer lifespan & healthspan via mitophagy and DNA repair (based on mice studies)
- Decreased risk of heart disease via reversing age-related arterial dysfunction and improved overall cardiac health (based on mice studies)
- Decreased aging of the skin
Lifestyle factors that decrease NAD+ levels:
- Optimal mitochondrial functioning
- Circadian rhythm mismatches
- Chronic inflammation and oxidative stress
- Constant caloric surplus (eating too much all the time) – higher NADH, lower NAD+
- Elevated blood sugar and insulin levels
- Chronic alcohol use
How it works?
1. 15-Minute Phone Consultation
2. New Client Visit and Lab Work
3. Review of Laboratoy Tests
4. Monitoring and Lab Visits
Possible consequences of NAD+ deficiency:
- Impaired immune system function
- Accelerated aging
- Mitochondrial dysfunction
- Disturbed circadian clocks (with aging)
- Increased carcinogenesis and risk for cancer
- Increased risk for insulin resistance and the development of diabetes
- Increased risk for obesity
- Increased risk for non-alcoholic fatty liver disease
- Increased risk for neurodegenerative disorders
- Increased risk for heart & kidney failure
Best ways to increase NAD+ levels in the body:
- Practice regular (intermittent) fasting and caloric restriction
- Activate ketogenesis in the body and have regular glucose restriction periods
- Exercise regularly
- Practice heat alteration
- Supplement with NAD+ precursors Nicotinamide riboside (NR): optimal dose 300 mg per day
- Increased risk for insulin resistance and the development of diabetes
- Nicotinamide mononucleotide (NMN): optimal dose 250–500 mg per day
- Use with trimethyl glycine (TMG) for optimal methylation process
- Niacinamide (NAM): optimal dose 250–500 mg per day
- Nicotinic acid (NA): optimal dose 250–500 mg per day
